St. Mark the Evangelist Catholic Church is located in New Tampa, just minutes north of the junction of Rte. I-75 and SR581 (Bruce B. Downs Blvd.) .

From the South take I-75 to exit 56 (Bruce B. Downs Blvd). Travel north approx. 1.8 miles to Cross Creek/ New Tampa Blvd.  Bear right onto Cross Creek Blvd. just before the light. Travel  about 1/2 mile.  Church is on the left.

From the North take Rte. I-75 to Rte. 54. Head East (left) about .3 miles to SR 581 (Bruce B. Downs Blvd.). Turn right onto Bruce B. Downs Blvd. and travel southwest approx 6.8 miles. Turn left onto Cross Creek Blvd. Travel about .5 miles.  Church is on the left.